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Who was studied 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals; replicated in Up to 319,677 individuals.
The effect
Each copy of the A allele shifted the measure 0.0223 mg dl-1 higher (95% confidence interval 0.016-0.028); p = 1 × 10−13.
How common The A allele had a frequency of about 23% in the people studied.
Where it sits Chromosome 3, band 3q26.2 — in an intron of SLC2A2.
What each result means
A/ATwo copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
Nature genetics · 2018 · PMID 30275531 · open access
Questions about rs11720145
What is rs11720145?
rs11720145 is a single position in the genome, in or near the SLC2A2 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11720145 linked to?
On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.
Does rs11720145 affect how medicines work?
SLC2A2 carries pharmacogenomic findings for Metformin. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs11720145 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11720145 come from?
GWAS Catalog, Nature genetics 2018, PMID:30275531. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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