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Who was studied 405,540 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0175 higher (95% confidence interval 0.012-0.023); p = 7 × 10−9.
How common The C allele had a frequency of about 95% in the people studied.
Where it sits Chromosome 21, band 21q22.2 — between genes, 18.8 kb from RPL23AP12.
What each result means
C/CTwo copies of the version the research linked to Height (baseline). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Height (baseline). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Height (baseline). This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40374629 · open access
Questions about rs117160808
What is rs117160808?
rs117160808 is a single position in the genome, in or near the near RPL23AP12 gene. Published research associates it with height (baseline). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs117160808 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs117160808 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs117160808 come from?
GWAS Catalog, Nature communications 2025, PMID:40374629. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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