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Sex hormone-binding globulin levels

near TRAIP · rs11715304

What the study found

Who was studied 158,000 British ancestry women.

The effect Each copy of the A allele shifted the measure 0.99 nmol/L lower (95% confidence interval 0.7-1.28); p = 2 × 10−11.

How common The A allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 3, band 3p21.31 — between genes, 4.7 kb from TRAIP.

What each result means

A/A Two copies of the version the research linked to Sex hormone-binding globulin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Sex hormone-binding globulin levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Sex hormone-binding globulin levels. This is the starting point the study compared everyone against.
Source

Questions about rs11715304

What is rs11715304?

rs11715304 is a single position in the genome, in or near the near TRAIP gene. Published research associates it with sex hormone-binding globulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11715304 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11715304 come from?

GWAS Catalog, Science advances 2021, PMID:34321204. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sex hormone-binding globulin levels (rs11715304). MyGeneLog™. https://www.mygenelog.com/variants/rs11715304

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