Sensitive

Breast cancer

NEK10 · rs11715126

Where this position leads

Condition: Breast Cancer

rs11715126 Condition: Breast Cancer Breast Cancer Condition rs11715126 rs11715126 NEK10

What the study found

Who was studied 394,626 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.111 lower (95% confidence interval 0.081-0.141); p = 1 × 10−13.

How common The A allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 3, band 3p24.1 — in an intron of NEK10.

What each result means

A/A Two copies of the version the research linked to Breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Breast cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Breast cancer. This is the starting point the study compared everyone against.
Source

Questions about rs11715126

What is rs11715126?

rs11715126 is a single position in the genome, in or near the NEK10 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11715126 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs11715126 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11715126 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Breast cancer (rs11715126). MyGeneLog™. https://www.mygenelog.com/variants/rs11715126

← See all variants