Standard

Body mass index

NRXN3 · rs117116987

Where this position leads

Condition: Childhood Body Mass Index

rs117116987 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs117116987 rs117116987 NRXN3

What the study found

Who was studied 1,122,049 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0292 lower (95% confidence interval 0.021-0.038); p = 1 × 10−11.

Where it sits Chromosome 14, band 14q31.1 — in an intron of NRXN3.

What each result means

A/A No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs117116987

What is rs117116987?

rs117116987 is a single position in the genome, in or near the NRXN3 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs117116987 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs117116987 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117116987 come from?

GWAS Catalog, Nature communications 2022, PMID:36581621. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body mass index (rs117116987). MyGeneLog™. https://www.mygenelog.com/variants/rs117116987

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