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Verbal learning

NT5DC2 · rs11711421

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 28,909 European ancestry individuals; replicated in 3,853 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 6.07 z score higher; p = 1 × 10⁻⁹.

How common The T allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 3, band 3p21.1 — in an intron of NT5DC2.

What each result means

C/C No copy of the version the research linked to Verbal learning. This is the starting point the study compared everyone against.

C/T One copy of the version the research linked to Verbal learning. That is a smaller link than two copies.

T/T Two copies of the version the research linked to Verbal learning. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning

Lahti J, Tuominen S, Yang Q, Pergola G, Ahmad S, Amin N, Armstrong NJ, Beiser A, Bey K, Bis JC, Boerwinkle E, Bressler J

and 112 more — show all

Campbell A, Campbell H, Chen Q, Corley J, Cox SR, Davies G, De Jager PL, Derks EM, Faul JD, Fitzpatrick AL, Fohner AE, Ford I, Fornage M, Gerring Z, Grabe HJ, Grodstein F, Gudnason V, Simonsick E, Holliday EG, Joshi PK, Kajantie E, Kaprio J, Karell P, Kleineidam L, Knol MJ, Kochan NA, Kwok JB, Leber M, Lam M, Lee T, Li S, Loukola A, Luck T, Marioni RE, Mather KA, Medland S, Mirza SS, Nalls MA, Nho K, O'Donnell A, Oldmeadow C, Painter J, Pattie A, Reppermund S, Risacher SL, Rose RJ, Sadashivaiah V, Scholz M, Satizabal CL, Schofield PW, Schraut KE, Scott RJ, Simino J, Smith AV, Smith JA, Stott DJ, Surakka I, Teumer A, Thalamuthu A, Trompet S, Turner ST, van der Lee SJ, Villringer A, Völker U, Wilson RS, Wittfeld K, Vuoksimaa E, Xia R, Yaffe K, Yu L, Zare H, Zhao W, Zhao W, Ames D, Attia J, Bennett DA, Brodaty H, Chasman DI, Goldman AL, Hayward C, Ikram MA, Jukema JW, Kardia SLR, Lencz T, Loeffler M, Mattay VS, Palotie A, Psaty BM, Ramirez A, Ridker PM, Riedel-Heller SG, Sachdev PS, Saykin AJ, Scherer M, Schofield PR, Sidney S, Starr JM, Trollor J, Ulrich W, Wagner M, Weir DR, Wilson JF, Wright MJ, Weinberger DR, Debette S, Eriksson JG, Mosley TH Jr, Launer LJ, van Duijn CM, Deary IJ, Seshadri S, Räikkönen K

Molecular psychiatry · 2022 · PMID 35974141 · open access

Questions about rs11711421

What is rs11711421?

rs11711421 is a single position in the genome, in or near the NT5DC2 gene. Published research associates it with verbal learning. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11711421 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11711421 come from?

GWAS Catalog, Molecular psychiatry 2022, PMID:35974141. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Verbal learning (rs11711421). MyGeneLog™. https://www.mygenelog.com/variants/rs11711421

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