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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,718 European ancestry cases, 2,944 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.35 lower; p = 7 × 10−12.
How common The T allele had a frequency of about 46% in the people studied.
Where it sits Chromosome 3, band 3p22.1 — between genes, 9 kb from MOBP.
What each result means
C/CNo copy of the version the research linked to Progressive supranuclear palsy. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Progressive supranuclear palsy. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Progressive supranuclear palsy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Molecular neurodegeneration · 2024 · PMID 39152475 · open access
Questions about rs11708828
What is rs11708828?
rs11708828 is a single position in the genome, in or near the near MOBP gene. Published research associates it with progressive supranuclear palsy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11708828 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11708828 come from?
GWAS Catalog, Molecular neurodegeneration 2024, PMID:39152475. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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