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UBA7177 abundance in stool

SYNPR · rs11706534

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 5,959 Finnish ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0599 higher (95% confidence interval 0.041-0.078); p = 3 × 10⁻¹⁰.

How common The A allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 3, band 3p14.2 — in an intron of SYNPR.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of UBA7177 abundance in stool compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with UBA7177 abundance in stool.

G/G Published research associates this genotype with typical/baseline likelihood of UBA7177 abundance in stool — no copies of the reported risk allele.

Source

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

Qin Y, Havulinna AS, Liu Y, Jousilahti P, Ritchie SC, Tokolyi A, Sanders JG, Valsta L, Brożyńska M, Zhu Q, Tripathi A, Vázquez-Baeza Y

and 9 more — show all

Loomba R, Cheng S, Jain M, Niiranen T, Lahti L, Knight R, Salomaa V, Inouye M, Méric G

Nature genetics · 2022 · PMID 35115689

Questions about rs11706534

What is rs11706534?

rs11706534 is a single position in the genome, in or near the SYNPR gene. Published research associates it with uba7177 abundance in stool. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11706534 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11706534 come from?

GWAS Catalog, Nature genetics 2022, PMID:35115689. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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UBA7177 abundance in stool (rs11706534). MyGeneLog™. https://www.mygenelog.com/variants/rs11706534

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