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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals; replicated in Up to 319,677 individuals.
The effect
Each copy of the T allele shifted the measure 0.026 mg dl-1 lower (95% confidence interval 0.019-0.033); p = 2 × 10−14.
How common The T allele had a frequency of about 71% in the people studied.
Where it sits Chromosome 3, band 3p21.1 — in an intron of DNAH1.
What each result means
C/CNo copy of the version the research linked to HDL cholesterol. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to HDL cholesterol. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to HDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2018 · PMID 30275531 · open access
Questions about rs11706108
What is rs11706108?
rs11706108 is a single position in the genome, in or near the DNAH1 gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11706108 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11706108 come from?
GWAS Catalog, Nature genetics 2018, PMID:30275531. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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