Sensitive

Response to antipsychotic treatment in schizophrenia

near WDR11 · rs117043183

Where this position leads

Condition: Schizophrenia

rs117043183 Condition: Schizophrenia Schizophrenia Condition rs117043183 rs117043183 near WDR11

What the study found

Who was studied 1,629 Chinese ancestry high-response cases, 485 Chinese ancestry low-response cases.

The effect Each copy of the A allele carried 0.40 times the odds of Response to antipsychotic treatment in schizophrenia (95% confidence interval 0.291-0.54); p = 5 × 10−9.

Where it sits Chromosome 10, band 10q26.12 — between genes, 25.1 kb from WDR11.

What each result means

A/A Two copies of the version the research linked to Response to antipsychotic treatment in schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Response to antipsychotic treatment in schizophrenia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Response to antipsychotic treatment in schizophrenia. This is the starting point the study compared everyone against.
Source

Questions about rs117043183

What is rs117043183?

rs117043183 is a single position in the genome, in or near the near WDR11 gene. Published research associates it with response to antipsychotic treatment in schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs117043183 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs117043183 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117043183 come from?

GWAS Catalog, Molecular psychiatry 2025, PMID:39562719. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Response to antipsychotic treatment in schizophrenia (rs117043183). MyGeneLog™. https://www.mygenelog.com/variants/rs117043183

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