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Total bilirubin levels

LDHB · rs117038277

What the study found

Who was studied 341,077 European ancestry individuals, 5,978 African ancestry individuals, 7,313 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0568 higher (95% confidence interval 0.043-0.071); p = 3 × 10−16.

Where it sits Chromosome 12, band 12p12.1 — in an intron of LDHB.

What each result means

G/G Two copies of the version the research linked to Total bilirubin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Total bilirubin levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Total bilirubin levels. This is the starting point the study compared everyone against.
Source

Questions about rs117038277

What is rs117038277?

rs117038277 is a single position in the genome, in or near the LDHB gene. Published research associates it with total bilirubin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs117038277 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs117038277 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total bilirubin levels (rs117038277). MyGeneLog™. https://www.mygenelog.com/variants/rs117038277

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