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C-reactive protein levels (MTAG)

near SOCS3 · rs116994828

Where this position leads

Condition: C-Reactive Protein Levels

rs116994828 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs116994828 rs116994828 near SOCS3

What the study found

Who was studied 575,531 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0355 higher (95% confidence interval 0.024-0.047); p = 5 × 10−10.

Where it sits Chromosome 17, band 17q25.3 — between genes, 5.3 kb from SOCS3.

What each result means

C/C No copy of the version the research linked to C-reactive protein levels (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to C-reactive protein levels (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to C-reactive protein levels (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs116994828

What is rs116994828?

rs116994828 is a single position in the genome, in or near the near SOCS3 gene. Published research associates it with c-reactive protein levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs116994828 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs116994828 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116994828 come from?

GWAS Catalog, Nature communications 2022, PMID:36376304. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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C-reactive protein levels (MTAG) (rs116994828). MyGeneLog™. https://www.mygenelog.com/variants/rs116994828

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