Who was studied 172,433 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0857 higher (95% confidence interval 0.064-0.107); p = 3 × 10−15.
How common The A allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 7, band 7q22.1 — in an intron of EPHB4.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mean corpuscular volume compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mean corpuscular volume.
G/GPublished research associates this genotype with typical/baseline likelihood of Mean corpuscular volume — no copies of the reported risk allele.
rs116979562 is a single position in the genome, in or near the EPHB4 gene. Published research associates it with mean corpuscular volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs116979562 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs116979562 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs116979562 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.