LRRC3 · rs116969723
Where this position leads
Condition: Intracranial Aneurysm
What the study found
Who was studied 250 Korean ancestry cases, 296 Korean ancestry controls.
The effect Each copy of the G allele carried 4.17 times the odds of Intracranial aneurysm (95% confidence interval 2.94-6.25); p = 4 × 10−15.
How common The G allele had a frequency of about 65% in the people studied.
Where it sits Chromosome 21, band 21q22.3 — a synonymous change in LRRC3.
rs116969723 is a single position in the genome, in or near the LRRC3 gene. Published research associates it with intracranial aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Intracranial Aneurysm. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Journal of clinical medicine 2019, PMID:30823506. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Intracranial aneurysm (rs116969723). MyGeneLog™. https://www.mygenelog.com/variants/rs116969723