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Feeling worry

PALM · rs116962250

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Feeling worry compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Feeling worry.

G/G Published research associates this genotype with typical/baseline likelihood of Feeling worry — no copies of the reported risk allele.

Source

Item-level analyses reveal genetic heterogeneity in neuroticism

Nagel M, Watanabe K, Stringer S, Posthuma D, van der Sluis S

Nature communications · 2018 · PMID 29500382 · open access

Questions about rs116962250

What is rs116962250?

rs116962250 is a single position in the genome, in or near the PALM gene. Published research associates it with feeling worry. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs116962250 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116962250 come from?

GWAS Catalog, Nat Commun 2018, PMID:29500382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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