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Cerebrospinal fluid AB1-42 levels

FRA10AC1 · rs116953792

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cerebrospinal fluid AB1-42 levels compared to the general population.

G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cerebrospinal fluid AB1-42 levels.

T/T Published research associates this genotype with typical/baseline likelihood of Cerebrospinal fluid AB1-42 levels — no copies of the reported risk allele.

Source

Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level

Li QS, Parrado AR, Samtani MN, Narayan VA

Alzheimer’s Disease Neuroimaging Initiative

PloS one · 2015 · PMID 26252872 · open access

Questions about rs116953792

What is rs116953792?

rs116953792 is a single position in the genome, in or near the FRA10AC1 gene. Published research associates it with cerebrospinal fluid ab1-42 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs116953792 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116953792 come from?

GWAS Catalog, PLoS One 2015, PMID:26252872. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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