FRA10AC1 · rs116953792
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied up to 189 European and other ancestry early mild cognitive impairment cases, up to 251 European and other ancestry late mild cognitive impairment cases, up to 121 European and other ancestry Alzheimer's disease cases, up to 215 European and other ancestry healthy controls; replicated in up to 3 European and other ancestry significant memory concern cases, up to 57 European and other ancestry early mild cognitive impairment cases, up to 61 European and other ancestry late mild cognitive impairment cases, up to 62 European and other ancestry Alzheimer's disease cases, up to 21 European and other ancestry healthy controls.
The effect Each copy of the G allele shifted the measure 0.239 higher; p = 8 × 10−11.
How common The G allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 10, band 10q23.33 — inside FRA10AC1.
rs116953792 is a single position in the genome, in or near the FRA10AC1 gene. Published research associates it with cerebrospinal fluid ab1-42 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS One 2015, PMID:26252872. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cerebrospinal fluid AB1-42 levels (rs116953792). MyGeneLog™. https://www.mygenelog.com/variants/rs116953792