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Dihexosylceramide (d18:1/20:0) levels

ST3GAL5 · rs11694145

What the study found

Who was studied 6,057 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 8 × 10−11.

Where it sits Chromosome 2, band 2p11.2 — in an intron of ST3GAL5.

What each result means

C/C No copy of the version the research linked to Dihexosylceramide (d18:1/20:0) levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Dihexosylceramide (d18:1/20:0) levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Dihexosylceramide (d18:1/20:0) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11694145

What is rs11694145?

rs11694145 is a single position in the genome, in or near the ST3GAL5 gene. Published research associates it with dihexosylceramide (d18:1/20:0) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11694145 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11694145 come from?

GWAS Catalog, Nature communications 2022, PMID:35668104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Dihexosylceramide (d18:1/20:0) levels (rs11694145). MyGeneLog™. https://www.mygenelog.com/variants/rs11694145

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