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TFPI2 protein levels

near BET1-AS1 · rs116913862

Where this position leads

Condition: Celiac Disease

rs116913862 Condition: Celiac Disease Celiac Disease Condition rs116913862 rs116913862 near BET1-AS1

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.358 lower (95% confidence interval 0.3-0.41); p = 5 × 10−43.

How common The C allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 7, band 7q21.3 — between genes, 110.1 kb from BET1-AS1.

What each result means

C/C Two copies of the version the research linked to TFPI2 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to TFPI2 protein levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to TFPI2 protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs116913862

What is rs116913862?

rs116913862 is a single position in the genome, in or near the near BET1-AS1 gene. Published research associates it with tfpi2 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs116913862 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs116913862 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116913862 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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TFPI2 protein levels (rs116913862). MyGeneLog™. https://www.mygenelog.com/variants/rs116913862

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