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Urinary microalbumin levels

CUBN · rs116867125

Where this position leads

Condition: Gout

rs116867125 Condition: Gout Gout Condition rs116867125 rs116867125 CUBN

What the study found

Who was studied 102,944 European ancestry individuals, 2,679 African ancestry individuals, 2,560 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0961 higher (95% confidence interval 0.066-0.126); p = 4 × 10−10.

Where it sits Chromosome 10, band 10p13 — in an intron of CUBN.

What each result means

A/A Two copies of the version the research linked to Urinary microalbumin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Urinary microalbumin levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Urinary microalbumin levels. This is the starting point the study compared everyone against.
Source

Questions about rs116867125

What is rs116867125?

rs116867125 is a single position in the genome, in or near the CUBN gene. Published research associates it with urinary microalbumin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs116867125 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs116867125 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116867125 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urinary microalbumin levels (rs116867125). MyGeneLog™. https://www.mygenelog.com/variants/rs116867125

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