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Hearing difficulty/problems: I am completely deaf (UKB data field 2247_99)

near GJB6 · rs116855998

What the study found

Who was studied 106 European ancestry cases, 437,661 European ancestry controls.

The effect Each copy of the G allele shifted the measure 12.4 higher (95% confidence interval 9.42-15.48); p = 8 × 10−16.

How common The G allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 13, band 13q12.11 — between genes, 3.7 kb from GJB6.

What each result means

A/A No copy of the version the research linked to Hearing difficulty/problems: I am completely deaf (UKB data field 2247_99). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Hearing difficulty/problems: I am completely deaf (UKB data field 2247_99). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Hearing difficulty/problems: I am completely deaf (UKB data field 2247_99). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs116855998

What is rs116855998?

rs116855998 is a single position in the genome, in or near the near GJB6 gene. Published research associates it with hearing difficulty/problems: i am completely deaf (ukb data field 2247_99). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs116855998 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116855998 come from?

GWAS Catalog, Nature genetics 2021, PMID:34737426. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hearing difficulty/problems: I am completely deaf (UKB data field 2247_99) (rs116855998). MyGeneLog™. https://www.mygenelog.com/variants/rs116855998

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