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Vertex-wise cortical surface area

CALCRL · rs11685426

What the study found

Who was studied 33,748 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 15.4 z score higher; p = 3 × 10−53.

How common The A allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 2, band 2q32.1 — in an intron of CALCRL.

What each result means

A/A Two copies of the version the research linked to Vertex-wise cortical surface area. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Vertex-wise cortical surface area. That is a smaller link than two copies.
G/G No copy of the version the research linked to Vertex-wise cortical surface area. This is the starting point the study compared everyone against.
Source

Questions about rs11685426

What is rs11685426?

rs11685426 is a single position in the genome, in or near the CALCRL gene. Published research associates it with vertex-wise cortical surface area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11685426 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11685426 come from?

GWAS Catalog, Science advances 2021, PMID:34910505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Vertex-wise cortical surface area (rs11685426). MyGeneLog™. https://www.mygenelog.com/variants/rs11685426

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