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Who was studied 312,888 European ancestry individuals, 5,568 African ancestry individuals, 6,685 South Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0165 higher (95% confidence interval 0.011-0.022); p = 3 × 10−10.
Where it sits Chromosome 2, band 2p11.2 — in an intron of TCF7L1.
What each result means
A/ATwo copies of the version the research linked to Serum phosphate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Serum phosphate levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Serum phosphate levels. This is the starting point the study compared everyone against.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs11684211
What is rs11684211?
rs11684211 is a single position in the genome, in or near the TCF7L1 gene. Published research associates it with serum phosphate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11684211 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs11684211 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11684211 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 5122Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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