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Lactate dehydrogenase levels

LDHA · rs116841148

What the study found

Who was studied 98,585 Icelandic ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.198 lower; p = 3 × 10−11.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 11, band 11p15.1 — a missense change in LDHA.

What each result means

G/G No copy of the version the research linked to Lactate dehydrogenase levels. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Lactate dehydrogenase levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Lactate dehydrogenase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs116841148

What is rs116841148?

rs116841148 is a single position in the genome, in or near the LDHA gene. Published research associates it with lactate dehydrogenase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs116841148 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116841148 come from?

GWAS Catalog, Nature communications 2016, PMID:26838040. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lactate dehydrogenase levels (rs116841148). MyGeneLog™. https://www.mygenelog.com/variants/rs116841148

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