DNMT3A · rs11683424
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 234,502 European ancestry individuals; replicated in 100,442 European ancestry individuals.
The effect The reported allele is C; the catalogue records no effect size ; p = 1 × 10−11.
How common The C allele had a frequency of about 82% in the people studied.
Where it sits Chromosome 2, band 2p23.3 — in an intron of DNMT3A.
rs11683424 is a single position in the genome, in or near the DNMT3A gene. Published research associates it with neutrophil-to-lymphocyte ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, American journal of human genetics 2021, PMID:34469753. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Neutrophil-to-lymphocyte ratio (rs11683424). MyGeneLog™. https://www.mygenelog.com/variants/rs11683424