Familial combined hyperlipidemia defined by Dutch criteria
DOCK7 · rs1168132
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 17,485 British ancestry cases, 331,737 British ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.174 lower (95% confidence interval 0.15-0.2); p = 5 × 10−49.
How common The T allele had a frequency of about 35% in the people studied.
Where it sits Chromosome 1, band 1p31.3 — in an intron of DOCK7.
What each result means
A/ANo copy of the version the research linked to Familial combined hyperlipidemia defined by Dutch criteria. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Familial combined hyperlipidemia defined by Dutch criteria. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Familial combined hyperlipidemia defined by Dutch criteria. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs1168132 is a single position in the genome, in or near the DOCK7 gene. Published research associates it with familial combined hyperlipidemia defined by dutch criteria. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1168132 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1168132 come from?
GWAS Catalog, Atherosclerosis 2022, PMID:34906840. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Familial combined hyperlipidemia defined by Dutch criteria (rs1168132). MyGeneLog™. https://www.mygenelog.com/variants/rs1168132