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Low fluorescent percentage of reticulocytes

CERKL · rs11680383

What the study found

Who was studied 39,470 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0553 SD units lower (95% confidence interval 0.041-0.07); p = 2 × 10−13.

How common The C allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 2, band 2q31.3 — in an intron of CERKL.

What each result means

C/C Two copies of the version the research linked to Low fluorescent percentage of reticulocytes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Low fluorescent percentage of reticulocytes. That is a smaller link than two copies.
T/T No copy of the version the research linked to Low fluorescent percentage of reticulocytes. This is the starting point the study compared everyone against.
Source

Questions about rs11680383

What is rs11680383?

rs11680383 is a single position in the genome, in or near the CERKL gene. Published research associates it with low fluorescent percentage of reticulocytes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11680383 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11680383 come from?

GWAS Catalog, Nature communications 2023, PMID:37596262. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Low fluorescent percentage of reticulocytes (rs11680383). MyGeneLog™. https://www.mygenelog.com/variants/rs11680383

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