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Primary dysmenorrhea

near IL1A · rs11676014

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 1,186 Taiwanese Han Chinese ancestry cases, 24,020 Taiwanese Han Chinese ancestry controls.

The effect Each copy of the G allele carried 1.32 times the odds of Primary dysmenorrhea (95% confidence interval 1.22-1.44); p = 7 × 10⁻¹⁰.

How common The G allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 2, band 2q14.1 — between genes, 16.8 kb from IL1A.

What each result means

A/A No copy of the version the research linked to Primary dysmenorrhea. This is the starting point the study compared everyone against.

A/G One copy of the version the research linked to Primary dysmenorrhea. That is a smaller link than two copies.

G/G Two copies of the version the research linked to Primary dysmenorrhea. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Genome-wide association study of primary dysmenorrhea in the Taiwan Biobank validates associations near the NGF and IL1 gene loci

Lee CC, Lee MG, Huang IH, Tan J, McCaw ZR, Su KY, Hsu TC, Huang RYJ, Kuo PH, Chen SC

National Taiwan University Hospital, Health Data Science Research Group

Journal of human genetics · 2022 · PMID 35351958

Questions about rs11676014

What is rs11676014?

rs11676014 is a single position in the genome, in or near the near IL1A gene. Published research associates it with primary dysmenorrhea. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11676014 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11676014 come from?

GWAS Catalog, Journal of human genetics 2022, PMID:35351958. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Primary dysmenorrhea (rs11676014). MyGeneLog™. https://www.mygenelog.com/variants/rs11676014

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