Sensitive

Schizophrenia

ZNF311 · rs116757206

Where this position leads

Condition: Schizophrenia

rs116757206 Condition: Schizophrenia Schizophrenia Condition rs116757206 rs116757206 ZNF311

What the study found

Who was studied 14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls.

The effect Each copy of the G allele carried 1.24 times the odds of Schizophrenia (95% confidence interval 1.2-1.28); p = 1 × 10−25.

Where it sits Chromosome 6, band 6p22.1 — between genes, 6.5 kb from LOC105375002.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Schizophrenia — no copies of the reported risk allele.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Schizophrenia.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Schizophrenia compared to the general population.
Source

Questions about rs116757206

What is rs116757206?

rs116757206 is a single position in the genome, in or near the ZNF311 gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs116757206 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs116757206 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116757206 come from?

GWAS Catalog, Schizophr Bull 2018, PMID:30285260. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (rs116757206). MyGeneLog™. https://www.mygenelog.com/variants/rs116757206

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