Sensitive

Inflammatory bowel disease

KIR2DL1 · rs11672983

Where this position leads

Condition: Inflammatory Bowel Disease

rs11672983 Condition: Inflammatory Bowel Disease Inflammatory Bowel Disease Condition rs11672983 rs11672983 KIR2DL1

What the study found

Who was studied 12,924 European ancestry cases, 21,442 European ancestry controls; replicated in 25,683 European ancestry cases, 17,015 European ancestry controls.

The effect Each copy of the A allele carried 1.09 times the odds of Inflammatory bowel disease (95% confidence interval 1.055-1.119); p = 7 × 10−11.

How common The A allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 19, band 19q13.42 — between genes, 2.5 kb from RNU6-222P.

What each result means

A/A Two copies of the version the research linked to Inflammatory bowel disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Inflammatory bowel disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Inflammatory bowel disease. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs11672983

What is rs11672983?

rs11672983 is a single position in the genome, in or near the KIR2DL1 gene. Published research associates it with inflammatory bowel disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11672983 linked to?

On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs11672983?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs11672983 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11672983 come from?

GWAS Catalog, Nature 2012, PMID:23128233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Inflammatory bowel disease (rs11672983). MyGeneLog™. https://www.mygenelog.com/variants/rs11672983

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