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Who was studied 100,453 Chinese Han ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.358 higher (95% confidence interval 0.25-0.47); p = 3 × 10−11.
How common The C allele had a frequency of about 64% in the people studied.
Where it sits Chromosome 19, band 19p13.11 — in an intron of MYO9B.
What each result means
C/CTwo copies of the version the research linked to Diastolic blood pressure (BMI adjusted). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Diastolic blood pressure (BMI adjusted). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Diastolic blood pressure (BMI adjusted). This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 39048560 · open access
Questions about rs11669463
What is rs11669463?
rs11669463 is a single position in the genome, in or near the MYO9B gene. Published research associates it with diastolic blood pressure (bmi adjusted). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11669463 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs11669463 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11669463 come from?
GWAS Catalog, Nature communications 2024, PMID:39048560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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