0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 762,151 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 7.8 z-score higher; p = 6 × 10−15.
How common The G allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 2, band 2q33.2 — in an intron of WDR12.
What each result means
A/ANo copy of the version the research linked to Heart failure (MTAG). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Heart failure (MTAG). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Heart failure (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
NPJ genomic medicine · 2025 · PMID 41022758 · open access
Questions about rs116678869
What is rs116678869?
rs116678869 is a single position in the genome, in or near the WDR12 gene. Published research associates it with heart failure (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs116678869 linked to?
On MyGeneLog this position is linked to Heart Failure. The research behind each link, and its sources, are set out on that condition page.
Does having rs116678869 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs116678869 come from?
GWAS Catalog, NPJ genomic medicine 2025, PMID:41022758. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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