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Medication use (thyroid preparations)

KIAA1683 · rs11666808

Where this position leads

Condition: Medication Use as a Genetic Trait

rs11666808 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs11666808 rs11666808 KIAA1683

What the study found

Who was studied 24,832 European ancestry cases, 280,750 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0734 lower (95% confidence interval 0.055-0.092); p = 9 × 10−15.

How common The T allele had a frequency of about 37% in the people studied.

Where it sits Chromosome 19, band 19p13.11 — in an intron of IQCN.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Medication use (thyroid preparations) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (thyroid preparations).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (thyroid preparations) compared to the general population.
Source

Questions about rs11666808

What is rs11666808?

rs11666808 is a single position in the genome, in or near the KIAA1683 gene. Published research associates it with medication use (thyroid preparations). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11666808 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs11666808 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11666808 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (thyroid preparations) (rs11666808). MyGeneLog™. https://www.mygenelog.com/variants/rs11666808

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