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Sex hormone-binding globulin levels adjusted for BMI

ZNF573 · rs11666245

What the study found

Who was studied 368,929 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0166 higher (95% confidence interval 0.013-0.021); p = 7 × 10−20.

How common The G allele had a frequency of about 95% in the people studied.

Where it sits Chromosome 19, band 19q13.12 — a missense change in ZNF573.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Sex hormone-binding globulin levels adjusted for BMI — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sex hormone-binding globulin levels adjusted for BMI.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sex hormone-binding globulin levels adjusted for BMI compared to the general population.
Source

Questions about rs11666245

What is rs11666245?

rs11666245 is a single position in the genome, in or near the ZNF573 gene. Published research associates it with sex hormone-binding globulin levels adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11666245 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11666245 come from?

GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sex hormone-binding globulin levels adjusted for BMI (rs11666245). MyGeneLog™. https://www.mygenelog.com/variants/rs11666245

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