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Cognitive performance

DCC · rs11662271

Where this position leads

Condition: Educational Attainment

rs11662271 Condition: Educational Attainment Educational Attainment Condition rs11662271 rs11662271 DCC

What the study found

Who was studied 257,841 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0232 higher (95% confidence interval 0.018-0.029); p = 4 × 10−16.

How common The T allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 18, band 18q21.2 — in an intron of DCC.

What each result means

C/C No copy of the version the research linked to Cognitive performance. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Cognitive performance. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Cognitive performance. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11662271

What is rs11662271?

rs11662271 is a single position in the genome, in or near the DCC gene. Published research associates it with cognitive performance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11662271 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs11662271 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11662271 come from?

GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cognitive performance (rs11662271). MyGeneLog™. https://www.mygenelog.com/variants/rs11662271

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