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Who was studied 20,427 African ancestry individuals; replicated in Up to 16,436 African American individuals.
The effect
Each copy of the C allele shifted the measure 0.053 higher (95% confidence interval 0.035-0.071); p = 6 × 10−10.
How common The C allele had a frequency of about 70% in the people studied.
Where it sits Chromosome 17, band 17q23.3 — in an intron of LOC101927898.
What ClinVar records
ClassificationBenign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2021-06-19.
ClinVar record 1181474NM_002401.5(MAP3K3):c.710+81G>C
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CTwo copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Height. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Height. This is the starting point the study compared everyone against.
PLoS genetics · 2011 · PMID 21998595 · open access
Questions about rs11658329
What is rs11658329?
rs11658329 is a single position in the genome, in or near the MAP3K3 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11658329 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs11658329 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11658329 come from?
GWAS Catalog, PLoS Genet 2011, PMID:21998595. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 4722126223126Reads by AI crawlersClaude2ChatGPT2Google · Gemini1Perplexity2Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others26Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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