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Eosinophil cationic protein levels and Eosinophil-derived neurotoxin levels

ARHGAP25 · rs116571378

What the study found

Who was studied 1,018 European ancestry individuals; replicated in 153 French-Canadian founder ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 4 × 10−10.

How common The T allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 2, band 2p13.3 — in an intron of ARHGAP25.

What each result means

C/C No copy of the version the research linked to Eosinophil cationic protein levels and Eosinophil-derived neurotoxin levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Eosinophil cationic protein levels and Eosinophil-derived neurotoxin levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Eosinophil cationic protein levels and Eosinophil-derived neurotoxin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs116571378

What is rs116571378?

rs116571378 is a single position in the genome, in or near the ARHGAP25 gene. Published research associates it with eosinophil cationic protein levels and eosinophil-derived neurotoxin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs116571378 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116571378 come from?

GWAS Catalog, The Journal of allergy and clinical immunology 2022, PMID:35671886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Eosinophil cationic protein levels and Eosinophil-derived neurotoxin levels (rs116571378). MyGeneLog™. https://www.mygenelog.com/variants/rs116571378

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