A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Parkinson's disease compared to the general population. (GWAS Catalog, Genes (Basel) 2021, PMID:34064523)
A/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Parkinson's disease. (GWAS Catalog, Genes (Basel) 2021, PMID:34064523)
T/TPublished research associates this genotype with typical/baseline likelihood of Parkinson's disease — no copies of the reported risk allele. (GWAS Catalog, Genes (Basel) 2021, PMID:34064523)
rs11653889 is a single position in the genome, in or near the HASPIN gene. Published research associates it with parkinson's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11653889 linked to?
On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs11653889 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11653889 come from?
GWAS Catalog, Genes (Basel) 2021, PMID:34064523. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.