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Who was studied 129,270 European ancestry cases, 108,357 European ancestry controls; replicated in 17,140 European ancestry cases, 61,850 European ancestry controls.
The effect
Each copy of the G allele carried 1.03 times the odds of Insomnia symptoms (never/rarely vs. usually) (95% confidence interval 1.02-1.05); p = 6 × 10−16.
How common The G allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 17, band 17q21.31 — between genes, 2.2 kb from HEXIM2-AS2.
What each result means
C/CNo copy of the version the research linked to Insomnia symptoms (never/rarely vs. usually). This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Insomnia symptoms (never/rarely vs. usually). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Insomnia symptoms (never/rarely vs. usually). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2019 · PMID 30804566 · open access
Questions about rs11651809
What is rs11651809?
rs11651809 is a single position in the genome, in or near the HEXIM2/LOC339192 gene. Published research associates it with insomnia symptoms (never/rarely vs. usually). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11651809 linked to?
On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.
Does having rs11651809 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11651809 come from?
GWAS Catalog, Nature genetics 2019, PMID:30804566. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 192413Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple4China (ByteDance, Huawei, Baidu…)0Others13Total19Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Insomnia symptoms (never/rarely vs. usually) (rs11651809). MyGeneLog™. https://www.mygenelog.com/variants/rs11651809