Sensitive

Type 1 diabetes

PRR15L · rs11651753

Where this position leads

Condition: Type 1 Diabetes

rs11651753 Condition: Type 1 Diabetes Type 1 Diabetes Condition rs11651753 rs11651753 PRR15L

What the study found

Who was studied 18,942 European ancestry cases, 501,638 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0869 lower (95% confidence interval 0.059-0.115); p = 1 × 10−9.

How common The T allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 17, band 17q21.32 — in an intron of PRR15L.

What each result means

C/C No copy of the version the research linked to Type 1 diabetes. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Type 1 diabetes. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11651753

What is rs11651753?

rs11651753 is a single position in the genome, in or near the PRR15L gene. Published research associates it with type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11651753 linked to?

On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs11651753 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11651753 come from?

GWAS Catalog, Nature 2021, PMID:34012112. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 1 diabetes (rs11651753). MyGeneLog™. https://www.mygenelog.com/variants/rs11651753

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