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3-phenylpropionate hydrocinnamate levels

ACSM5 · rs11647589

What the study found

Who was studied 6,182 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.03 higher (95% confidence interval 0.02-0.04); p = 3 × 10−11.

How common The A allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 16, band 16p12.3 — in an intron of ACSM5.

What each result means

A/A Two copies of the version the research linked to 3-phenylpropionate hydrocinnamate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to 3-phenylpropionate hydrocinnamate levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to 3-phenylpropionate hydrocinnamate levels. This is the starting point the study compared everyone against.
Source

Questions about rs11647589

What is rs11647589?

rs11647589 is a single position in the genome, in or near the ACSM5 gene. Published research associates it with 3-phenylpropionate hydrocinnamate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11647589 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11647589 come from?

GWAS Catalog, Nature genetics 2014, PMID:24816252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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3-phenylpropionate hydrocinnamate levels (rs11647589). MyGeneLog™. https://www.mygenelog.com/variants/rs11647589

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