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Adiponectin levels

CDH13 · rs11646213

Where this position leads

What the study found

Who was studied up to 60,465 European ancestry individuals, up to 2,568 East Asian ancestry individuals, up to 3,271 African American individuals, up to 1,435 Hispanic individuals.

The effect Each copy of the T allele shifted the measure 0.0418 higher; p = 3 × 10⁻¹¹.

How common The T allele had a frequency of about 56% in the people studied.

Where it sits Chromosome 16, band 16q23.3 — between genes, 17.9 kb from CDH13.

What each result means

A/A No copy of the version the research linked to Adiponectin levels. This is the starting point the study compared everyone against.

A/T One copy of the version the research linked to Adiponectin levels. That is a smaller link than two copies.

T/T Two copies of the version the research linked to Adiponectin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

Spracklen CN, Karaderi T, Yaghootkar H, Schurmann C, Fine RS, Kutalik Z, Preuss MH, Lu Y, Wittemans LBL, Adair LS, Allison M, Amin N

and 92 more — show all

Auer PL, Bartz TM, Blüher M, Boehnke M, Borja JB, Bork-Jensen J, Broer L, Chasman DI, Chen YI, Chirstofidou P, Demirkan A, van Duijn CM, Feitosa MF, Garcia ME, Graff M, Grallert H, Grarup N, Guo X, Haesser J, Hansen T, Harris TB, Highland HM, Hong J, Ikram MA, Ingelsson E, Jackson R, Jousilahti P, Kähönen M, Kizer JR, Kovacs P, Kriebel J, Laakso M, Lange LA, Lehtimäki T, Li J, Li-Gao R, Lind L, Luan J, Lyytikäinen LP, MacGregor S, Mackey DA, Mahajan A, Mangino M, Männistö S, McCarthy MI, McKnight B, Medina-Gomez C, Meigs JB, Molnos S, Mook-Kanamori D, Morris AP, de Mutsert R, Nalls MA, Nedeljkovic I, North KE, Pennell CE, Pradhan AD, Province MA, Raitakari OT, Raulerson CK, Reiner AP, Ridker PM, Ripatti S, Roberston N, Rotter JI, Salomaa V, Sandoval-Zárate AA, Sitlani CM, Spector TD, Strauch K, Stumvoll M, Taylor KD, Thuesen B, Tönjes A, Uitterlinden AG, Venturini C, Walker M, Wang CA, Wang S, Wareham NJ, Willems SM, Willems van Dijk K, Wilson JG, Wu Y, Yao J, Young KL, Langenberg C, Frayling TM, Kilpeläinen TO, Lindgren CM, Loos RJF, Mohlke KL

American journal of human genetics · 2019 · PMID 31178129

Questions about rs11646213

What is rs11646213?

rs11646213 is a single position in the genome, in or near the CDH13 gene. Published research associates it with adiponectin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11646213 linked to?

On MyGeneLog this position is linked to Adiponectin Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs11646213 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11646213 come from?

GWAS Catalog, American journal of human genetics 2019, PMID:31178129. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Adiponectin levels (rs11646213). MyGeneLog™. https://www.mygenelog.com/variants/rs11646213

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