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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 446,237 European ancestry individuals; replicated in 7,612 African ancestry individuals, 10,095 South Asian ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0138 higher (95% confidence interval 0.0095-0.0181); p = 4 × 10−10.
How common The T allele had a frequency of about 91% in the people studied.
Where it sits Chromosome 16, band 16p11.2 — in a non-coding transcript of ASPHD1.
What each result means
C/CNo copy of the version the research linked to Urinary sodium excretion. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Urinary sodium excretion. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Urinary sodium excretion. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2019 · PMID 31409800 · open access
Questions about rs11646118
What is rs11646118?
rs11646118 is a single position in the genome, in or near the KCTD13 gene. Published research associates it with urinary sodium excretion. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11646118 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11646118 come from?
GWAS Catalog, Nature communications 2019, PMID:31409800. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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