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Who was studied 3,846 Finnish ancestry cases, 28,881 Finnish ancestry controls, 3,846 non-Scandinavian ancestry cases, 28,881 non-Scandinavian ancestry controls, 3,846 British ancestry cases, 28,881 British ancestry controls.
The effect
Each copy of the T allele carried 1.51 times the odds of Peripheral artery disease in diabetes (95% confidence interval 1.32-1.74); p = 3 × 10−9.
How common The T allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 4, band 4q22.1 — in an intron of CCSER1.
What each result means
C/CNo copy of the version the research linked to Peripheral artery disease in diabetes. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Peripheral artery disease in diabetes. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Peripheral artery disease in diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Circulation. Genomic and precision medicine · 2021 · PMID 34601942 · open access
Questions about rs116405693
What is rs116405693?
rs116405693 is a single position in the genome, in or near the CCSER1 gene. Published research associates it with peripheral artery disease in diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs116405693 linked to?
On MyGeneLog this position is linked to Peripheral Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs116405693 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs116405693 come from?
GWAS Catalog, Circulation. Genomic and precision medicine 2021, PMID:34601942. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 725Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others5Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Peripheral artery disease in diabetes (rs116405693). MyGeneLog™. https://www.mygenelog.com/variants/rs116405693