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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 288,127 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0278 lower (95% confidence interval 0.019-0.036); p = 3 × 10−10.
How common The A allele had a frequency of about 44% in the people studied.
Where it sits Chromosome 17, band 17p13.1 — between genes, 5 kb from ASGR1.
What each result means
A/ATwo copies of the version the research linked to LDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to LDL cholesterol levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to LDL cholesterol levels. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 36333282 · open access
Questions about rs116403919
What is rs116403919?
rs116403919 is a single position in the genome, in or near the near ASGR1 gene. Published research associates it with ldl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs116403919 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs116403919 come from?
GWAS Catalog, Nature communications 2022, PMID:36333282. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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