Sensitive

Coronary artery disease

MORF4L1 · rs11637783

Where this position leads

Condition: Coronary Artery Disease

rs11637783 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs11637783 rs11637783 MORF4L1

What the study found

Who was studied 34,541 cases, 261,984 controls; replicated in 88,192 cases, 162,544 controls.

The effect Each copy of the T allele shifted the measure 0.074 higher (95% confidence interval 0.06-0.088); p = 1 × 10−30.

How common The T allele had a frequency of about 57% in the people studied.

Where it sits Chromosome 15, band 15q25.1 — inside MORF4L1.

What each result means

C/C No copy of the version the research linked to Coronary artery disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Coronary artery disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11637783

What is rs11637783?

rs11637783 is a single position in the genome, in or near the MORF4L1 gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11637783 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs11637783 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11637783 come from?

GWAS Catalog, Circulation research 2018, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Coronary artery disease (rs11637783). MyGeneLog™. https://www.mygenelog.com/variants/rs11637783

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