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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.
The effect
Each copy of the C allele shifted the measure 0.05 mmol/L lower (95% confidence interval 0.03-0.07); p = 2 × 10−13.
Where it sits Chromosome 5, band 5p13.2 — between genes, 12.9 kb from IL7R.
What each result means
C/CTwo copies of the version the research linked to Acetate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Acetate levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Acetate levels. This is the starting point the study compared everyone against.
Nature genetics · 2025 · PMID 41044249 · open access
Questions about rs116347259
What is rs116347259?
rs116347259 is a single position in the genome, in or near the near IL7R gene. Published research associates it with acetate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs116347259 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs116347259 come from?
GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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