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Testosterone levels

near HCG22 · rs116325030

What the study found

Who was studied 235,579 European ancestry females.

The effect Each copy of the A allele shifted the measure 0.101 higher (95% confidence interval 0.075-0.127); p = 6 × 10−14.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 6.7 kb from HCG22.

What each result means

A/A Two copies of the version the research linked to Testosterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Testosterone levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Testosterone levels. This is the starting point the study compared everyone against.
Source

Questions about rs116325030

What is rs116325030?

rs116325030 is a single position in the genome, in or near the near HCG22 gene. Published research associates it with testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs116325030 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116325030 come from?

GWAS Catalog, Nature genetics 2025, PMID:40229599. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Testosterone levels (rs116325030). MyGeneLog™. https://www.mygenelog.com/variants/rs116325030

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