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Keloid

NEDD4 · rs11632096

Where this position leads

Condition: Keloid

rs11632096 Condition: Keloid Keloid Condition rs11632096 rs11632096 NEDD4

What the study found

Who was studied 4,086 European ancestry cases, 1,278,496 European ancestry controls, 1,055 East Asian ancestry cases, 177,671 East Asian ancestry controls, 2,696 African American or Afro-Caribbean cases, 136,842 African American or Afro-Caribbean controls.

The effect Each copy of the A allele carried 0.83 times the odds of Keloid (95% confidence interval 0.797402268-0.854358828); p = 1 × 10−27.

Where it sits Chromosome 15, band 15q21.3 — in an intron of NEDD4.

What each result means

A/A Two copies of the version the research linked to Keloid. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Keloid. That is a smaller link than two copies.
G/G No copy of the version the research linked to Keloid. This is the starting point the study compared everyone against.
Source

Questions about rs11632096

What is rs11632096?

rs11632096 is a single position in the genome, in or near the NEDD4 gene. Published research associates it with keloid. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11632096 linked to?

On MyGeneLog this position is linked to Keloid. The research behind each link, and its sources, are set out on that condition page.

Does having rs11632096 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11632096 come from?

GWAS Catalog, Nature communications 2025, PMID:40835838. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Keloid (rs11632096). MyGeneLog™. https://www.mygenelog.com/variants/rs11632096

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