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Insulin-like growth factor 1 levels

MIDEAS · rs11626364

Where this position leads

Condition: Gout

rs11626364 Condition: Gout Gout Condition rs11626364 rs11626364 MIDEAS

What the study found

Who was studied 340,567 European ancestry individuals, 5,974 African ancestry individuals, 7,283 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0256 lower (95% confidence interval 0.019-0.032); p = 1 × 10−14.

Where it sits Chromosome 14, band 14q24.3 — in an intron of MIDEAS.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Insulin-like growth factor 1 levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Insulin-like growth factor 1 levels.
T/T Published research associates this genotype with typical/baseline likelihood of Insulin-like growth factor 1 levels — no copies of the reported risk allele.
Source

Questions about rs11626364

What is rs11626364?

rs11626364 is a single position in the genome, in or near the MIDEAS gene. Published research associates it with insulin-like growth factor 1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11626364 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs11626364 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11626364 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Insulin-like growth factor 1 levels (rs11626364). MyGeneLog™. https://www.mygenelog.com/variants/rs11626364

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