Sensitive

Diverticular disease

FAM155A · rs11619840

Where this position leads

Condition: Diverticular Disease

rs11619840 Condition: Diverticular Disease Diverticular Disease Condition rs11619840 rs11619840 FAM155A

What the study found

Who was studied 27,444 British ancestry cases, 382,284 British ancestry controls.

The effect Each copy of the A allele shifted the measure 0.00417 lower; p = 2 × 10−9.

How common The A allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 13, band 13q33.3 — in an intron of NALF1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diverticular disease compared to the general population.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diverticular disease.
C/C Published research associates this genotype with typical/baseline likelihood of Diverticular disease — no copies of the reported risk allele.
Source

Questions about rs11619840

What is rs11619840?

rs11619840 is a single position in the genome, in or near the FAM155A gene. Published research associates it with diverticular disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11619840 linked to?

On MyGeneLog this position is linked to Diverticular Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs11619840 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11619840 come from?

GWAS Catalog, Nat Genet 2018, PMID:30177863. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diverticular disease (rs11619840). MyGeneLog™. https://www.mygenelog.com/variants/rs11619840

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